Charles E. Sing

Postdoctoral Fellow at Northwestern University, Olvera de la Cruz group

email: charles.sing at northwestern dot edu

Ph.D. Materials Science & Engineering and PPST
Massachusetts Institute of Technology, 2008-2012

M.S. Macromolecular Science & Engineering
Case Western Reserve University, 2007-2008

B.S.E. Polymer Science & Engineering
Case Western Reserve University, 2004-2008


I am interested in the single-chain dynamics of biopolymers in the presence of fluid flows and surfaces, particularly in the context of blood clotting.


Viola, Piano


Curriculum Vitae


2013   Best PhD Thesis Award, DMSE MIT
2012   International Institute for Nanotechnology Postdoctoral Fellowship
2012   2011 Graduate Student Teaching Award
2012   APS DPOLY Padden Award Finalist
2011   Materials Research Society Graduate Student Silver Award
2009   National Defense Science and Engineering Graduate Fellowship
2008   Dupont-MIT Alliance Presidential Fellowship


21.   Multiple-binding-site mechanism explains concentration-dependent unbinding rates of DNA-binding proteins
C.E. Sing, M. Olvera de la Cruz, J.F. Marko
Nuc. Acids Res. In Press, (2013).

20.   Ion correlation-induced phase separation in polyelectrolyte blends
C.E. Sing, J.W. Zwanikken, M. Olvera de la Cruz
ACS Macro Lett. 2, 1042-1046 (2013).

19.   Interfacial behavior in polyelectrolyte blends: Hybrid liquid-state integral equation and self consistent field theory study
C.E. Sing, J.W. Zwanikken, M. Olvera de la Cruz
Phys. Rev. Lett. 111, 168303 (2013).

18.   Effect of ion-ion correlations on polyelectrolyte gel collapse and reentrant swelling
C.E. Sing, J.W. Zwanikken, M. Olvera de la Cruz
Macromolecules 46, 5053-5065 (2013).

17.   von Willebrand adhesion to surfaces at high shear rates is controlled by long-lived bonds
C.E. Sing, J.G. Selvidge, A. Alexander-Katz
Biophys. J. 105, 1475-1481 (2013).

16.   Designed Molecular Mechanics Using Self-Associating Polymers
C.E. Sing, A. Alexander-Katz
Soft Matter 8, 11871-11879 (2012).

15.   Force spectroscopy of self-associating homopolymers
C.E. Sing, A. Alexander-Katz
Macromolecules 45(16), 6704-6718 (2012).

14.   Conformational dynamics and internal friction in homo-polymer globules: equilibrium vs. non-equilibrium simulations
T.R. Einert, C.E. Sing, A. Alexander-Katz, R.R. Netz
Eur. Phys. J. E. 34, 130 (2011).

13.   Giant non-monotonic stretching response of a self-associating polymer in shear flow
C.E. Sing, A. Alexander-Katz
Phys. Rev. Lett. 107, 198302 (2011).

12.   Theory of tethered polymers in shear flow: the strong stretching limit
C.E. Sing, A. Alexander-Katz
Macromolecules 44(22), 9020-9028 (2011).

11.   Equilibrium structure and dynamics of self-associating single polymers
C.E. Sing, A. Alexander-Katz
Macromolecules 44(17), 6962-6971 (2011).

10.   Non-monotonic hydrodynamic lift force on highly-elongated polymers near surfaces
C.E. Sing, A. Alexander-Katz
Europhys. Lett. 95, 48001 (2011).

9.   Dynamics of collapsed polymers under the simultaneous influence of elongational and shear flows
C.E. Sing, A. Alexander-Katz
J. Chem. Phys. 135, 014902 (2011).

8.   Probing structural and dynamical transitions in polymer globules by force
C.E. Sing, T.R. Einert, R.R. Netz, A. Alexander-Katz
Phys. Rev. E 83(4), 040801(R) (2011).

7.   Self-Assembled Micro-Walkers
S.E. Moran, C.E. Sing, A. Alexander-Katz
Proc. of the 2nd Eur. Conf. on Microfluidics (2010).

6.   Multidimensional targeting: using physical and chemical forces in unison
R.C. Van Lehn, C.E. Sing, H. Chen, A. Alexander-Katz
Curr. Pharm. Biotechnol. 11, 320-332 (2010).

5.   Globule-Stretch Transitions of Collapsed Polymers in Elongational Flow Fields
C.E. Sing, A. Alexander-Katz
Macromolecules 43(7), 3532-3541 (2010).

4.   Elongational flow induces the unfolding of von Willebrand factor at physiological flow rates
C.E. Sing, A. Alexander-Katz
Biophys. J. 98(9), L35-L37 (2010).

3.   Controlled surface-induced flows from the motion of self-assembled colloidal walkers
C.E. Sing, L. Schmid, M.F. Schneider, T. Franke, A. Alexander-Katz
Proc. Natl. Acad. Sci. USA 107(2), 535-540 (2010).

2.   Time-Temperature indicators for high temperature applications
C.E. Sing, J. Kunzelman, C. Weder
J. Mat. Chem. 19, 104-110 (2009).

1.   Threshold Temperature Sensors with Tunable Properties
B.R. Crenshaw, J. Kunzelman, C.E. Sing, C. Ander, C. Weder
Macromol. Chem. Phys. 208, 572-580 (2007).

Department of Materials Science and Engineering MIT